Fig. 4

Scatter plots for mtDNA copy number and mRNA expression of TFAM, POLG, PGC-1α, c-myc, and CS genes in ALL patients and healthy controls. A MtDNA copy number analysis in ALL patients and healthy controls (p = 0.0012). B TFAM gene expression in ALL patients and healthy controls (p = 0.0024). C POLG gene expression in ALL patients and healthy controls p < 0.0001). D PGC-1α gene expression in ALL patients and healthy controls (p = 0.7999). E c-myc gene expression in ALL patients and healthy controls (p = 0.0149). F CS gene expression in ALL patients and healthy controls (p = 0.0095); (* p < 0.05, ** p < 0.01, *** p < 0.001, Mann-Whitney U test)