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Table 1 Summary of the NIR organic dyes

From: A brief review of non-invasive brain imaging technologies and the near-infrared optical bioimaging

Class

Name

Ex.

Emi.

Abs.

Q.Y.

Biomedical Applications

Ref.

Polymethine (Cyanine)

Cy3

550

570

309

0.15

Biotechnologies (labeling, analysis, biomedical imagings)

–

Cy5

650

670

409

0.27

Cy7

743

767

512

0.28

ICG

788

830

800

0.04

Clinical angiography, laparoscopic surgery

Kim et al. 2018

CDnir7

806

821

 

0.14

Bioimaging – inflammation

Kang et al. 2014

TiNIR

805

825

 

0.09

Bioimaging - lung tunor initiating cells

Kim et al. 2019b

Polymethine (Sulfur)

IR-26

785, 808

~ 1050

950

~ 0.05

Bioimaging - Lymphatic systems

Wang et al. 2019

IR-1061

980

1074

~ 1000

~ 0.02

Bioimaging - Inner organs and blood vessels

Tao et al. 2013

IRBTP-B

950

~ 1000

905

0.001

Detection - drug-induced hepatotoxicity

Zhao et al. 2021

D-A-D (benzobisthadiazoles)

H1

785

~ 1100

600–1000

0.02

Biomaging - tumor; Imaging-guided surgery

Sun et al. 2017

Q8

808

1020–1150

600–1000

0.0001

Bioimaging - tumor, Imaging-guided surgery

Qu et al. 2019

IR-FP8

808

~ 1000

808

0.04

Videorate imaging - hindlimb vessels of mice

Ma et al. 2020

TPB-AZO

 

909

690

0.22

Detection - cardiac cyle and heart rate

Zhang et al. 2020

BPST

715

897

347–711

0.06

Bioimaging - blood, lymphatic vessels, and tumors

Wu et al. 2019

HLZ-BTED

785

~ 1000

~ 805

0.002

Detection - gastrointestinal function and diseases

Lin et al. 2019

XA1

808

~ 1000

400–780

0.15

Bioimaging - limb and cerebral vessels

Xu et al. 2020

2TT-oC6B

808

1014

700

0.11

Bioimaging - brain inflammation

Liu et al. 2020